Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270823 | 0.95 | AKR1B1 (0.55) | AKR1B1HTTABCC4LMNAGAA | |
| SCHEMBL6135997 | 0.90 | AKR1B1 (0.50) | AKR1B1HTTABCC4LMNAGAA | |
| SCHEMBL28148401 | 0.84 | NPSR1 (0.64) | HTTGAATSHRNPSR1ALDH1A1 | |
| SCHEMBL75883 | 0.84 | NPSR1 (0.64) | HTTGAATSHRNPSR1ALDH1A1 | |
| SCHEMBL75885 | 0.84 | NPSR1 (0.64) | HTTGAATSHRNPSR1ALDH1A1 | |
| Urea SCHEMBL23005263 | 0.82 | NPSR1 (0.61) | HTTGAATSHRNPSR1ALDH1A1 | |
| SCHEMBL28023499 | 0.82 | NPSR1 (0.61) | HTTGAATSHRNPSR1ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL28272945 | 0.82 | NPSR1 (0.61) | HTTGAATSHRNPSR1ALDH1A1 | |
| Water SCHEMBL27782253 | 0.82 | NPSR1 (0.61) | HTTGAATSHRNPSR1ALDH1A1 | |
| Phenylacetic Acid SCHEMBL2146253 | 0.80 | AKR1B1 (0.81) | AKR1B1HTTABCC4LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087956-A1 | Urea compounds as inhibitors for vla-4 | ASTRAZENECA AB (SE) | 2003-05-08 | — | — | US | disclosed |
| EP-1252152-A1 | UREA COMPOUNDS AS INHIBITORS FOR VLA-4 | AstraZeneca AB (SE) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001053279-A1 | UREA COMPOUNDS AS INHIBITORS FOR VLA-4 | ASTRAZENECA AB (SE) | 2001-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087956-A1 | Urea compounds as inhibitors for vla-4 | VCAM1, ITGA4, ITGB4 | AKR1B1 3900/4885HTT 4349/4885ABCC4 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.