Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL449891 | 0.87 | MAPK1 (0.66) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL7249392 | 0.85 | POLB (0.54) | MAPK1LMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL428355 | 0.84 | MAPK1 (1.00) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL5658852 | 0.83 | MAPK1 (0.84) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL16010904 | 0.83 | MAPK1 (0.84) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL5657260 | 0.81 | LMNA (1.00) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL8656369 | 0.81 | MAPK1 (0.73) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL13593351 | 0.80 | LMNA (0.74) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL9183154 | 0.80 | MAPK1 (0.90) | MAPK1LMNAPOLBCYP1A2CYP2C9 | |
| SCHEMBL24316125 | 0.79 | MAPK1 (0.76) | MAPK1LMNAPOLBCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630577-B2 | Useful for producing bioconjugates | PROLINX, INC. | 2003-10-07 | — | — | US | disclosed |
| EP-1264833-A2 | 1,2-Phenylenediboronic acid reagents and complexes | PROLINX, INC. (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020038004-A1 | 1,2-phenylenediboronic acid reagents and complexes | PROLINX, INC. | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038004-A1 | 1,2-phenylenediboronic acid reagents and complexes | BCR, MGST1, SULT1E1 | MAPK1 944/4885LMNA 4240/4885POLB 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.