Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.50 |
| ▸ | LSS | P48449 | 4/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.41 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.41 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.41 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.41 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.41 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.41 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.41 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.41 |
| ▸ | INPP5D | Q92835 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512355 | 0.88 | USP2 (0.56) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL5095966 | 0.88 | USP2 (0.56) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL4303282 | 0.88 | USP2 (0.56) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL26642363 | 0.88 | USP2 (0.56) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL337078 | 0.88 | USP2 (0.56) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL7246364 | 0.88 | NR1H4 (0.50) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL30106435 | 0.85 | LSS (0.49) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL30106436 | 0.85 | LSS (0.49) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL7245217 | 0.85 | LSS (0.49) | NR1I2LSSNR1H4MEN1USP2 | |
| SCHEMBL11418481 | 0.85 | LSS (0.49) | NR1I2LSSNR1H4MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030004148-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004148-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | NR1I2 596/4885LSS 1593/4885NR1H4 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.