SCHEMBL724949

SCHEMBL724949

NCCCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
PLG P00747 1/20 0.39
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
SLC6A2 P23975 1/20 0.39
RECQL P46063 1/20 0.39
SLC6A3 Q01959 1/20 0.39
PAOX Q6QHF9 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
BLM P54132 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15773249 1.00 KMT2A (0.39) KMT2AALDH1A1MEN1PLGLMNA
SCHEMBL26198454 1.00 KMT2A (0.39) KMT2AALDH1A1MEN1PLGLMNA
Bromide SCHEMBL5681816 0.98 KMT2A (0.38) KMT2AALDH1A1MEN1PLGLMNA
SCHEMBL18768942 0.98 CYP2D6 (0.38) KMT2AALDH1A1MEN1PLGLMNA
SCHEMBL8829865 0.93 CYP1A2 (0.41) KMT2ALMNATHRBSMN1; SMN2CYP2D6
SCHEMBL13192974 0.91 SLC6A5 (0.39) KMT2AALDH1A1MEN1PLGLMNA
SCHEMBL905722 0.91 SMN1; SMN2 (0.42) KMT2AALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL4960230 0.91 SMN1; SMN2 (0.42) KMT2AALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL379163 0.91 SMN1; SMN2 (0.42) KMT2AALDH1A1SMN1; SMN2HPGDHTT
SCHEMBL1870550 0.91 SMN1; SMN2 (0.42) KMT2AALDH1A1SMN1; SMN2HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5998616-A Biocatalyst for the conversion of carbonyl compounds to their β-unsaturated derivatives using molecular oxygen as the oxidant THE UNIVERSITY OF MICHIGAN (US) 1999-12-07 US claimed
CN-112263682-B PCSK 9-targeting antisense oligomers and conjugates 罗氏创新中心哥本哈根有限公司 2024-08-20 CN disclosed
EP-4357463-A2 APPLICATION OF EPIGENETIC CHROMSOMAL INTERACTIONS IN CANCER DIAGNOSTICS Oxford BioDynamics PLC (GB) 2024-04-24 EP disclosed
EP-3704274-B1 GENETIC REGULATION OF IMMUNORESPONSE BY CHROMOSOME INTERACTIONS Oxford BioDynamics PLC (GB) 2024-04-17 EP disclosed
EP-3548633-B1 APPLICATION OF EPIGENETIC CHROMSOMAL INTERACTIONS IN CANCER DIAGNOSTICS Oxford BioDynamics PLC (GB) 2024-01-24 EP disclosed
EP-4301874-A1 CHROMOSOME INTERACTION MARKERS Oxford BioDynamics PLC (GB) 2024-01-10 EP disclosed
EP-4274910-A1 CHROMOSOME INTERACTIONS Oxford BioDynamics PLC (GB) 2023-11-15 EP disclosed
US-20230279476-A1 NOVEL ACRYLATE DERIVATIVES AND USES THEREOF EXPANSION TECHNOLOGIES (US) 2023-09-07 US disclosed
US-20230279476-A1 NOVEL ACRYLATE DERIVATIVES AND USES THEREOF EXPANSION TECHNOLOGIES (US) 2023-09-07 US disclosed
EP-3452612-B1 DETECTION OF CHROMOSOME INTERACTION RELEVANT TO BREAST CANCER Oxford BioDynamics PLC (GB) 2023-08-23 EP disclosed
WO-1999038014-A1 ASSESSING RISK FOR INTEGRIN ANTAGONIST/AGONIST MEDIATED DISEASES DU PONT PHARMACEUTICALS COMPANY (US) 1999-07-29 WO disclosed
EP-0882233-A1 METHOD AND DEVICE FOR TREATMENT BY COMPLEXING OF A LIQUID MEDIUM BIO MERIEUX (FR) 1998-12-09 EP disclosed
WO-1998051435-A1 FULLY-COATED, UNIFORM-SIZED METALLIC PARTICLES TANG WEIXIN (US) 1998-11-19 WO disclosed
WO-1998028436-A1 SCREENING ASSAY FOR PROTEOLYSIS INHIBITORS ZENECA LIMITED (GB) 1998-07-02 WO disclosed
WO-1998015832-A1 METHOD AND DEVICE FOR TREATMENT BY COMPLEXING OF A LIQUID MEDIUM BIO MERIEUX (FR) 1998-04-16 WO disclosed
EP-0525821-A2 Methods and structures employing non-radioactive chemically-labeled polynucleotide probes ENZO BIOCHEM, INC. (US) 1993-02-03 EP disclosed
WO-1992003732-A2 COMPOSITIONS AND METHODS FOR ENHANCED BINDING IN BIOLOGICAL ASSAYS BIOPROBE INTERNATIONAL, INC. (US) 1992-03-05 WO disclosed
EP-0330221-A2 End labeled nuceotide probe ENZO BIOCHEM, INC. (US) 1989-08-30 EP disclosed
WO-1989002933-A1 NON-NUCLEOTIDE REAGENTS FOR SUBSTITUTING TERMINI OF OLIGONUCLEOTIDES ML TECHNOLOGY VENTURES, L.P. (US) 1989-04-06 WO disclosed
EP-0310312-A2 Non-nucleotide reagents for substituting termini of oligonucleotides M.L. TECHNOLOGY VENTURES, L.P. (US) 1989-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230279476-A1 NOVEL ACRYLATE DERIVATIVES AND USES THEREOF DCLRE1A, ACR, PHAX KMT2A 3464/4885ALDH1A1 2377/4885MEN1 4026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.