Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28164018 | 0.85 | ALDH1A1 (0.37) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL10795292 | 0.84 | ALDH1A1 (0.36) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL28219613 | 0.82 | GAA (0.39) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL1138886 | 0.81 | GAA (0.38) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL20815 | 0.79 | THRB (0.46) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL27727120 | 0.79 | ALOX15 (0.43) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL14976946 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL28623879 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL2476700 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TSHRGAAALOX15MGAM | |
| SCHEMBL744097 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635691-B2 | Containing filler and a polymerizable matrix | IVOCLAR VIVADENT AG (LI) | 2003-10-21 | — | — | US | disclosed |
| US-20020040075-A1 | Dental material containing a component which contracts during thermal treatment | IVOCLAR VIVADENT AG. | 2002-04-04 | — | — | US | disclosed |