SCHEMBL724973

SCHEMBL724973

O=C(O)Oc1cc(O)cc(O)c1C(=O)c1ccc(O)c(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 1/20 0.70
CA12 O43570 4/20 0.46
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA7 P43166 4/20 0.46
CA9 Q16790 4/20 0.46
CA14 Q9ULX7 4/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 2/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
PTGS2 P35354 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
FASN P49327 1/20 0.42
XDH P47989 1/20 0.41
SIRT1 Q96EB6 1/20 0.41
SLC22A6 Q4U2R8 1/20 0.40
SLC22A8 Q8TCC7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15773425 0.83 SYNJ2 (1.00) SYNJ2CA12CA1CA2CA7
Maclurin SCHEMBL29523046 0.81 SYNJ2 (0.69) SYNJ2CA12CA1CA2CA7
Maclurin SCHEMBL758337 0.81 SYNJ2 (0.69) SYNJ2CA12CA1CA2CA7
SCHEMBL29396136 0.80 SYNJ2 (0.56) SYNJ2CA12CA1CA2CA7
SCHEMBL17944269 0.80 SYNJ2 (0.56) SYNJ2CA12CA1CA2CA7
SCHEMBL11645189 0.78 CYP3A4 (0.52) SYNJ2KDM4EPOLBMAPTFASN
Gallic Acid SCHEMBL22117576 0.75 POLB (0.56) SYNJ2CA12CA1CA2CA7
SCHEMBL29071843 0.74 SYNJ2 (0.56) SYNJ2CA12CA1CA2CA7
SCHEMBL1758192 0.71 CA12 (0.68) SYNJ2CA12CA1CA2CA7
SCHEMBL8995644 0.70 MAOB (0.54) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130133108-A1 EXTRACTS FROM PIRIN+ AND PIRIN- PLANTS AND USES THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2013-05-23 US disclosed
WO-2012027609-A2 EXTRACTS FROM PIRIN+ AND PIRIN- PLANTS AND USES THEREOF THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2012-03-01 WO disclosed