Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.72 |
| ▸ | HRH2 | P25021 | 3/20 | 0.57 |
| ▸ | HRH1 | P35367 | 3/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.55 |
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | DRD3 | P35462 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4192075 | 0.86 | HRH4 (0.83) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL3858913 | 0.86 | HRH4 (0.64) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL11505298 | 0.86 | HRH4 (0.54) | HRH4HRH2HRH1HRH3DRD2 | |
| Hydrochloric Acid SCHEMBL3838758 | 0.85 | HRH4 (0.81) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL8930476 | 0.85 | HRH4 (0.67) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL9078990 | 0.85 | HRH4 (0.67) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL8930480 | 0.85 | HRH4 (0.67) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL140907 | 0.84 | HRH4 (1.00) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL4194509 | 0.84 | HRH4 (0.69) | HRH4HRH2HRH1HRH3DRD2 | |
| SCHEMBL7406087 | 0.84 | DRD3 (0.56) | HRH4HRH2HRH1HRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135042-A1 | Atypical antipsychotic agents having low affinity for the D2 Receptor | NEUROMOLECULAR, INC. (CA) | 2003-07-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135042-A1 | Atypical antipsychotic agents having low affinity for the D2 Receptor | OPRD1, HTR1A, DRD2 | HRH4 528/4885HRH2 541/4885HRH1 638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.