SCHEMBL7250554

SCHEMBL7250554

CCCOC(=O)OC(C)[C](C)OC(=O)OC(C)C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
LMNA P02545 2/20 0.33
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL577735 0.84 LMNA (0.42) TSHRLMNAHCAR2
SCHEMBL7245151 0.75 ALDH1A1 (0.41) TSHRHCAR2
SCHEMBL7250555 0.74 FAAH (0.36) TSHRLMNAHCAR2
Tert-Butyl Hydroperoxide SCHEMBL27806184 0.74 LMNA (0.35) TSHRLMNAHCAR2
SCHEMBL13133071 0.73 TSHR (0.46) TSHRLMNAHCAR2
SCHEMBL10011696 0.73 CA1 (0.37) TSHRLMNAHCAR2
SCHEMBL452059 0.72 ALDH1A1 (0.52) TSHRLMNAHCAR2
SCHEMBL10087932 0.71 LMNA (0.52) TSHRLMNAHCAR2
SCHEMBL15986332 0.71 HCAR2 (0.39) TSHRLMNAHCAR2
SCHEMBL8861415 0.70 HSD17B10 (0.38) TSHRLMNAHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030069204-A1 Strain of streptomyces SANKYO COMPANY LIMITED (JP) 2003-04-10 US disclosed
EP-0497978-A1 CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF Kyoto Pharmaceutical Industries, Ltd. (JP) 1992-08-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069204-A1 Strain of streptomyces O60361, CYP8B1, MRPS34 TSHR 3757/4885LMNA 3952/4885HCAR2 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.