Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 12/20 | 0.66 |
| ▸ | ADH1C | P00326 | 9/20 | 0.62 |
| ▸ | ADH4 | P08319 | 3/20 | 0.44 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651685 | 0.85 | ADH1A (0.58) | ADH1AADH1CADH4ADH1B | |
| SCHEMBL27363843 | 0.83 | ADH1A (0.63) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL9660553 | 0.79 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL6984253 | 0.79 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL9661004 | 0.79 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 | |
| Hydrochloric Acid SCHEMBL8308886 | 0.78 | ADH1A (0.96) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL7802361 | 0.77 | ADH1A (1.00) | ADH1AADH1CADH4ADH1B | |
| SCHEMBL9658881 | 0.76 | ADH1A (0.79) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL726395 | 0.76 | ADH1A (0.79) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL9660884 | 0.76 | ADH1A (0.79) | ADH1AADH1CADH4ADH1BADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |