SCHEMBL6984253

SCHEMBL6984253

CCCN(C=O)C1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADH1A P07327 12/20 1.00
ADH1C P00326 9/20 0.96
ADH4 P08319 3/20 0.58
ADH1B P00325 2/20 0.44
ADH7 P40394 1/20 0.33
DRD3 P35462 5/20 0.33
DRD2 P14416 2/20 0.33
DRD4 P21917 2/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9660553 1.00 ADH1A (1.00) ADH1AADH1CADH4ADH1BADH7
SCHEMBL9661004 1.00 ADH1A (1.00) ADH1AADH1CADH4ADH1BADH7
Hydrochloric Acid SCHEMBL8308886 0.98 ADH1A (0.96) ADH1AADH1CADH4ADH1BADH7
SCHEMBL7802361 0.98 ADH1A (1.00) ADH1AADH1CADH4ADH1BDRD3
Hydrochloric Acid SCHEMBL8303801 0.96 ADH1A (0.96) ADH1AADH1CADH4ADH1BDRD3
SCHEMBL8383244 0.96 ADH1A (0.96) ADH1AADH1CADH4ADH1BDRD3
SCHEMBL1678410 0.89
SCHEMBL9658881 0.88 ADH1A (0.79) ADH1AADH1CADH4ADH1BADH7
SCHEMBL726395 0.88 ADH1A (0.79) ADH1AADH1CADH4ADH1BADH7
SCHEMBL9660884 0.88 ADH1A (0.79) ADH1AADH1CADH4ADH1BADH7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390372-B1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2020-06-03 EP disclosed
EP-1027351-B1 PHENANTHROLINE DERIVATIVES FIBROGEN INC (US) 2003-12-03 EP disclosed
US-20010001101-A1 Phenanthroline derivatives ZENECA LIMITED 2001-05-10 US disclosed
US-6200974-B1 FOR PRODUCING AN ANTI-FIBROPROLIFERATIVE EFFECT ZENECA LIMITED (GB) 2001-03-13 US disclosed
US-5916898-A ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS ZENECA LIMITED (GB) 1999-06-29 US disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
WO-1997047599-A1 SUCCINAMIDE DERIVATIVES USEFUL AS TNF- AND/OR MMP INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-12-18 WO disclosed
US-5656604-A HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-08-12 US disclosed
US-5430022-A Endothelin antagonists; hypotensive agents; treatment for angina pectoris, brain disorders, asthma, renal failure FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1995-07-04 US disclosed
US-5284828-A Hypotensive agents FUJISAWA PHARMACEUTICAL CO. LTD. (JP) 1994-02-08 US disclosed
US-5224987-A Aqueous carriers with colors and tertiary amide penetrants E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-06 US disclosed
EP-0517262-A1 Trifluorothymidine derivatives, process for producing the same and anti-cancer agent containing the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-12-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010001101-A1 Phenanthroline derivatives H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, COL1A1, COL2A1 ADH1A 293/4885ADH1C 24/4885ADH4 1851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.