Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | HAT1 | O14929 | 4/20 | 0.41 |
| ▸ | EP300 | Q09472 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245070 | 0.90 | F2 (0.53) | F2BCHEACHEFNTAFNTB | |
| SCHEMBL7244643 | 0.88 | F2 (0.50) | F2BCHEACHEFNTAFNTB | |
| Hydrochloric Acid SCHEMBL7252424 | 0.88 | F2 (0.52) | F2BCHEACHECNR2CNR1 | |
| Hydrochloric Acid SCHEMBL7246507 | 0.87 | F2 (0.63) | F2BCHEACHE | |
| SCHEMBL7249259 | 0.82 | EPHX2 (0.48) | F2BCHEHAT1EP300CNR2 | |
| SCHEMBL7245210 | 0.82 | F2 (0.51) | F2BCHEACHEFNTAFNTB | |
| SCHEMBL7247840 | 0.81 | NSD2 (0.52) | F2CNR2CNR1HDAC1HDAC8 | |
| SCHEMBL7245646 | 0.80 | F2 (0.63) | F2HDAC1HDAC8HDAC6 | |
| SCHEMBL7245916 | 0.80 | F2 (0.46) | F2FNTAFNTBCNR2CNR1 | |
| SCHEMBL7249769 | 0.80 | HSD17B10 (0.47) | F2FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |