Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7244643 | 0.91 | F2 (0.50) | F2ALDH1A1FNTAFNTB | |
| SCHEMBL7246372 | 0.88 | PDK1 (0.51) | F2LMNAPDK1MAPTITK | |
| SCHEMBL7245210 | 0.87 | F2 (0.51) | F2FNTAFNTBITK | |
| SCHEMBL7245916 | 0.86 | F2 (0.46) | F2FNTAFNTBITK | |
| SCHEMBL7245070 | 0.84 | F2 (0.53) | F2FNTAFNTB | |
| SCHEMBL7245590 | 0.84 | CNR2 (0.45) | F2 | |
| SCHEMBL7244700 | 0.82 | F2 (0.48) | F2RECQLALDH1A1GAAITK | |
| SCHEMBL7247078 | 0.82 | F2 (0.51) | F2PDK1ITK | |
| SCHEMBL7245646 | 0.82 | F2 (0.63) | F2ITK | |
| SCHEMBL7246953 | 0.80 | F2 (0.46) | F2RECQLITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6512000-B1 | Aminocarbonyl- substituted benzimidazole derivatives for the treatment of diseases in which inhibition of tryptase is of therapeutic such as for treating an inflammatory or allergic disease | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-01-28 | — | — | US | disclosed |