Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.57 |
| ▸ | POLB | P06746 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.57 |
| ▸ | BLM | P54132 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252222 | 0.93 | MAPT (0.67) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL7252201 | 0.89 | MAPT (0.66) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL7252162 | 0.84 | MAPT (0.65) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL7252721 | 0.82 | MAPT (0.66) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL7252207 | 0.82 | MAPT (0.77) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL7252752 | 0.79 | ALDH1A1 (0.64) | MAPTTDP1TP53SMN1; SMN2GAA | |
| SCHEMBL15410142 | 0.78 | MAPT (0.68) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL7252736 | 0.77 | MAPT (0.76) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL28959059 | 0.75 | MAPT (0.91) | MAPTPOLBTDP1BLMTP53 | |
| SCHEMBL1074591 | 0.73 | MAPT (0.84) | MAPTPOLBTDP1BLMTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | claimed |
| WO-2003010147-A1 | ACIDIC QUINOLONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2003-02-06 | — | — | WO | disclosed |