Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038535 | 0.80 | PPARG (0.58) | ATMNPC1PPARGPPARA | |
| SCHEMBL7034794 | 0.79 | PPARG (0.57) | ATMNPC1PPARGPPARA | |
| Lithium Ion SCHEMBL7034789 | 0.73 | PPARG (0.68) | ATMNPC1PPARGPPARA | |
| SCHEMBL7036795 | 0.73 | PPARG (0.55) | ATMNPC1HTTRECQLPPARG | |
| SCHEMBL7252878 | 0.68 | PPARG (0.61) | TSHRCASP1SMN1; SMN2HTTPPARG | |
| SCHEMBL7252882 | 0.68 | PPARG (0.61) | TSHRCASP1SMN1; SMN2HTTPPARG | |
| SCHEMBL7252441 | 0.65 | PPARG (0.53) | TSHRCASP1SMN1; SMN2NPC1RECQL | |
| SCHEMBL29712519 | 0.64 | ALDH1A1 (0.58) | TSHRRARARARBPPARD | |
| SCHEMBL5063442 | 0.64 | SMN1; SMN2 (0.49) | TSHRCASP1SMN1; SMN2ATMNPC1 | |
| SCHEMBL8067440 | 0.62 | MAPT (0.58) | TSHRSMN1; SMN2MRGPRX4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | claimed |