Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21818348 | 0.87 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1KDM4ELMNAPRKAB2 | |
| SCHEMBL5063455 | 0.87 | THRB (0.47) | SMN1; SMN2THRBTHRAALDH1A1KDM4E | |
| SCHEMBL4689621 | 0.86 | PARP1 (0.46) | SMN1; SMN2THRBTHRAALDH1A1KDM4E | |
| SCHEMBL5068149 | 0.84 | THRB (0.45) | SMN1; SMN2THRBTHRAALDH1A1KDM4E | |
| SCHEMBL1750089 | 0.84 | THRB (0.60) | TSHRTHRBTHRAPLA2G2A | |
| SCHEMBL3417416 | 0.84 | KMT2A (0.54) | SMN1; SMN2TSHRCASP1THRBTHRA | |
| SCHEMBL3904366 | 0.82 | CA12 (0.52) | TSHRPLA2G2AALDH1A1PLA2G4APOLB | |
| SCHEMBL3417202 | 0.81 | THRB (0.64) | TSHRTHRBTHRAPLA2G2A | |
| SCHEMBL29492898 | 0.81 | THRB (0.64) | TSHRTHRBTHRAPLA2G2A | |
| SCHEMBL1994532 | 0.81 | THRA (0.47) | TSHRTHRBTHRAALDH1A1TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-07-03 | — | — | US | disclosed |
| EP-1867639-A1 | UREA DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
| EP-1867639-A1 | UREA DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161294-A1 | Urea derivative, medicinal composition containing the same, and medicinal use of these | AVPR2, UTS2R, GPR119 | SMN1; SMN2 3056/4885TSHR 191/4885CASP1 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.