Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | HTR7 | P34969 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699610 | 0.78 | ALDH1A1 (0.46) | — | |
| SCHEMBL6694944 | 0.78 | DRD2 (0.57) | NPC1HTR1AHTR7DRD2DRD4 | |
| SCHEMBL5743699 | 0.75 | ALOX15 (0.39) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL18011026 | 0.75 | ALOX15 (0.39) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL6961329 | 0.72 | NPC1 (0.60) | NPC1HTR1AHTR7 | |
| SCHEMBL6968950 | 0.72 | NPC1 (0.60) | NPC1HTR1AHTR7DRD2DRD4 | |
| SCHEMBL3121473 | 0.72 | NPC1 (0.60) | NPC1HTR1AHTR7DRD2DRD4 | |
| SCHEMBL8173559 | 0.72 | KDM4E (0.55) | NPC1HTR1ADRD2DRD4DRD3 | |
| SCHEMBL6954338 | 0.71 | NPC1 (0.59) | NPC1HTR1AHTR7DRD2DRD4 | |
| SCHEMBL24984562 | 0.71 | NPC1 (0.52) | NPC1HTR1AHTR7DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |