Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894403 | 0.79 | SIRT2 (0.48) | SMN1; SMN2SIRT2LMNA | |
| SCHEMBL3894083 | 0.78 | NPC1 (0.60) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL3889851 | 0.78 | SMN1; SMN2 (0.64) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL3894291 | 0.76 | SIRT2 (0.51) | RAB9ASMN1; SMN2NPC1TP53NPSR1 | |
| SCHEMBL3901088 | 0.75 | NPC1 (0.66) | RAB9ASMN1; SMN2NPC1TP53TSHR | |
| SCHEMBL3892664 | 0.75 | TSHR (0.58) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL3891472 | 0.74 | GLA (0.50) | RAB9ANPC1TP53NPSR1SIRT2 | |
| SCHEMBL3893324 | 0.70 | GLA (0.54) | RAB9ANPC1TP53NPSR1SIRT2 | |
| SCHEMBL3898264 | 0.66 | GAA (0.45) | RAB9ASMN1; SMN2NPC1TP53MAPT | |
| SCHEMBL4396673 | 0.65 | FPR2 (0.46) | RAB9ASMN1; SMN2NPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003010143-A1 | DIALKYLHYDROXYBENZOIC ACID DERIVATIVES CONTAINING METAL CHELATING GROUPS AND THEIR THERAPEUTIC USES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2003-02-06 | — | — | WO | disclosed |