Sugi Predict

Sugi Predict / Compounds / SCHEMBL3898264

SCHEMBL3898264

SCHEMBL3898264

CC(C)(C)c1cc(C(=O)Nc2ncncn2)cc(C(C)(C)C)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 2/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ LMNA P02545 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ ALOX5 P09917 2/20 0.40
▸ PTGS1 P23219 2/20 0.40
▸ PTGS2 P35354 2/20 0.40
▸ SMN1; SMN2 Q16637 4/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA1 P00915 1/20 0.39
▸ SYK P43405 1/20 0.39
▸ POLB P06746 1/20 0.38
▸ TYR P14679 1/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ TP53 P04637 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3891472 0.86 GLA (0.50) GAAALDH1A1TDP1LMNARECQL
SCHEMBL3895175 0.80 KMT2A (0.46) ALDH1A1TDP1LMNARECQLPOLB
SCHEMBL3889851 0.75 SMN1; SMN2 (0.64) GAAALDH1A1TDP1SMN1; SMN2NPSR1
SCHEMBL3894346 0.75 ALPL (0.64) SMN1; SMN2POLBNPC1RAB9AALPL
SCHEMBL12324390 0.75 GAA (0.53) GAAALDH1A1TDP1LMNARECQL
SCHEMBL3891550 0.74 GAA (0.41) GAAALDH1A1TDP1LMNARECQL
SCHEMBL3126822 0.74 ALDH1A1 (0.46) GAAALDH1A1TDP1LMNAALOX5
SCHEMBL3891438 0.74 SMN1; SMN2 (0.58) ALDH1A1LMNARECQLSMN1; SMN2POLB
SCHEMBL11636683 0.73 GAA (0.52) GAAALDH1A1TDP1LMNARECQL
SCHEMBL4799286 0.73 HDAC1 (0.52) GAAALDH1A1TDP1LMNARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7511034-B2 Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-03-31 — — US claimed
US-7229988-B2 Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-06-12 — — US claimed
US-20060116377-A1 Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses OH EU-GENE 2006-06-01 — — US claimed
CN-103969863-B Liquid crystal display device 三星显示有限公司 2018-09-25 — — CN disclosed
CN-108056532-A Knitted textile and shoe upper and manufacturing method thereof 耐克创新有限合伙公司 2018-05-22 — — CN disclosed
CN-107849307-A Additive agent mixture 巴斯夫欧洲公司 2018-03-27 — — CN disclosed
CN-103459569-B Lubricant compositions with improved non-Newtonian viscosity behavior 巴斯夫欧洲公司 2018-01-19 — — CN disclosed
CN-107250238-A Light stabilization of polyolefins film, band and monofilament 巴斯夫欧洲公司 2017-10-13 — — CN disclosed
CN-105694098-B A kind of additive for polymer 天津利安隆新材料股份有限公司 2017-09-15 — — CN disclosed
CN-107075202-A Use of organooxyimide salts as flame retardants, flame-retardant plastic compositions, method for the production thereof and moulded parts, paints or coatings 弗劳恩霍弗应用研究促进协会 2017-08-18 — — CN disclosed
CN-107001698-A Phosphorous organic epoxide acid imide is used as flame retardant of plastic agent and/or the purposes of stabilizer, fire-retardant and/or stable plastics composite, its preparation method, molded item, paint and coating 弗劳恩霍弗应用研究促进协会 2017-08-01 — — CN disclosed
CN-1252160-C Synergistic stabilizer compositions for color stable pigmented thermoplastic polymers in prolonged contact with water CLARIANT FINANCE BVI LTD (GB) 2006-04-19 — — CN disclosed
US-20040214827-A1 Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses SAM-SUNG ELECTRONICS CO., LTD. (KR) 2004-10-28 — — US disclosed
CN-1444624-A Synergistic stabilizer compositions for color stable pigmented thermoplastic polymers in prolonged contact with water CLARIANT FINANCE BVI LTD (VG) 2003-09-24 — — CN disclosed
CN-1074015-C Stabilizer cmbination CIBA GEIGY AG (CH) 2001-10-31 — — CN disclosed
CN-1067994-C Bisresorcinyltriazines CIBA GEIGY AG (CH) 2001-07-04 — — CN disclosed
CN-1041415-C 3-arylbenzofuranone stabilizers and uses thereof CIBA GEIGY AG (CH) 1998-12-30 — — CN disclosed
CN-1183410-A Hydroxyphenyltriazines CIBA SC HOLDING AG (CH) 1998-06-03 — — CN disclosed
CN-1176280-A Stabilizers for powder coatings CIBA SC HOLDING AG (CH) 1998-03-18 — — CN disclosed
CN-1135477-A Diphenolic ester derivative CIBA GEIGY AG (CH) 1996-11-13 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060116377-A1 Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses SOD1, DDO, LPO GAA 56/4885ALDH1A1 1086/4885TDP1 3678/4885
US-20040214827-A1 Dialkylhydroxybenzoic acid derivatives containing metal chelating groups and their therapeutic uses SOD1, DDO, LPO GAA 44/4885ALDH1A1 922/4885TDP1 3768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.