Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2232683 | 0.80 | GAA (0.62) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL6698448 | 0.80 | ALDH1A1 (0.61) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL6703230 | 0.79 | MAPT (0.61) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL3233096 | 0.78 | MEN1 (0.53) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL3128886 | 0.77 | CHRNA7 (0.58) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL7066698 | 0.76 | DRD4 (0.52) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL27918278 | 0.76 | MEN1 (0.51) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL29696209 | 0.76 | ALDH1A1 (0.51) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL6550343 | 0.76 | CHRNA7 (0.54) | MEN1ALDH1A1HTTKMT2ACHRNA7 | |
| SCHEMBL6550223 | 0.76 | KMT2A (0.51) | MEN1ALDH1A1HTTKMT2ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |