SCHEMBL7253674

SCHEMBL7253674

CCCCOC(=O)CNO

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
NAAA Q02083 1/20 0.52
ATM Q13315 1/20 0.48
FAAH O00519 2/20 0.47
DGKA P23743 1/20 0.47
HPGD P15428 2/20 0.45
TSHR P16473 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
PPARG P37231 1/20 0.44
NCOA2 Q15596 1/20 0.44
NCOA1 Q15788 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
NCOA3 Q9Y6Q9 1/20 0.44
RAD52 P43351 1/20 0.44
EPHX1 P07099 1/20 0.44
ACHE P22303 6/20 0.42
HCAR2 Q8TDS4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16057779 0.92 NAAA (0.64) NAAAFAAHDGKATSHRNPSR1
SCHEMBL21578651 0.85 ALDH1A1 (0.50) ALDH1A1NAAAATMFAAHDGKA
SCHEMBL8390838 0.84 ALDH1A1 (0.54) ALDH1A1NAAAATMFAAHDGKA
SCHEMBL807476 0.83 ALDH1A1 (0.52) ALDH1A1NAAAATMFAAHDGKA
SCHEMBL152233 0.81 ALDH1A1 (0.61) ALDH1A1NAAAATMFAAHDGKA
SCHEMBL10154353 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMFAAHDGKA
Hydrochloric Acid SCHEMBL7367029 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMFAAHDGKA
SCHEMBL1515500 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMFAAHDGKA
SCHEMBL17970767 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMFAAHDGKA
SCHEMBL9947101 0.81 ALDH1A1 (0.50) ALDH1A1NAAAATMFAAHDGKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003020709-A1 1,2-OXAZIN-3-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS SIMON FRASER UNIVERSITY (CA) 2003-03-13 WO disclosed