Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912809 | 0.83 | HTR2C (0.54) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL8390838 | 0.83 | ALDH1A1 (0.54) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL7253674 | 0.81 | ALDH1A1 (0.52) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL807476 | 0.81 | ALDH1A1 (0.52) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL152233 | 0.80 | ALDH1A1 (0.61) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL10154353 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL1515500 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL21578651 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NAAAATMFAAHDGKA | |
| Hydrochloric Acid SCHEMBL7367029 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NAAAATMFAAHDGKA | |
| SCHEMBL17970767 | 0.79 | ALDH1A1 (0.50) | ALDH1A1NAAAATMFAAHDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149632-A1 | GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY | THE MEDICINES COMPANY (US) | 2012-06-14 | — | — | US | disclosed |
| WO-2011019839-A2 | GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY | THE MEDICINES COMPANY (US) | 2011-02-17 | — | — | WO | disclosed |
| US-20100216834-A1 | HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2010-08-26 | — | — | US | disclosed |
| US-20080280945-A1 | Crystalline forms of an HIV integrase inhibitor | MERCK SHARP & DOHME CORP. | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216834-A1 | HIV INTEGRASE INHIBITORS | REV1, CDK9, INTS9 | ALDH1A1 2670/4885NAAA 2308/4885ATM 2689/4885 |
| US-20080280945-A1 | Crystalline forms of an HIV integrase inhibitor | TYMP, SAMHD1, ACIN1 | ALDH1A1 3635/4885NAAA 2928/4885ATM 1672/4885 |
| US-20120149632-A1 | GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS WITH IMPROVED SOLUBILITY | NGLY1, LGALS3BP, GYPA | ALDH1A1 4197/4885NAAA 906/4885ATM 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.