Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 5/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258292 | 0.94 | DGAT1 (0.48) | MCHR1DRD2PARP14DGAT1OPRK1 | |
| SCHEMBL7255884 | 0.90 | MCHR1 (0.59) | MCHR1DRD2DGAT1MCHR2SIGMAR1 | |
| SCHEMBL7255916 | 0.89 | MCHR1 (0.61) | MCHR1DRD2DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7258373 | 0.88 | MCHR1 (0.60) | MCHR1DRD2DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7259439 | 0.87 | MCHR1 (0.56) | MCHR1DRD2DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7254964 | 0.87 | MCHR1 (0.63) | MCHR1DRD2DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7260631 | 0.85 | MCHR1 (0.54) | MCHR1DRD2DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7255582 | 0.84 | MCHR1 (0.69) | MCHR1DGAT1MCHR2SIGMAR1CHRM4 | |
| SCHEMBL7260684 | 0.84 | DGAT1 (0.56) | MCHR1DRD2DGAT1OPRK1SIGMAR1 | |
| SCHEMBL7258185 | 0.83 | MCHR1 (0.68) | MCHR1DGAT1MCHR2SIGMAR1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087046-A1 | NOVEL AMINOTETRALINE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |