Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | MASP2 | O00187 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254370 | 0.84 | F2 (0.43) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7254368 | 0.84 | F2 (0.43) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7255198 | 0.76 | F2 (0.46) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL7255193 | 0.70 | F2 (0.39) | F2PRSS1PRSS2PRSS3MASP2 | |
| SCHEMBL30933792 | 0.68 | CYP1A2 (0.55) | ADRB2HTR1ACYP1A2CYP2D6KDM4E | |
| SCHEMBL7254246 | 0.67 | MEN1 (0.41) | F2CYP1A2KDM4EALDH1A1MEN1 | |
| SCHEMBL7254244 | 0.67 | MEN1 (0.41) | F2CYP1A2KDM4EALDH1A1MEN1 | |
| SCHEMBL7254326 | 0.67 | KDM4E (0.48) | CYP1A2CYP2D6KDM4EALDH1A1MEN1 | |
| SCHEMBL7255220 | 0.67 | KDM4E (0.48) | KDM4EALDH1A1MEN1KMT2APTGER1 | |
| SCHEMBL7260017 | 0.65 | KDM4E (0.46) | ADRB2HTR1AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011222-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2003-02-13 | — | — | WO | disclosed |