Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256181 | 0.87 | TACR2 (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7255372 | 0.87 | TACR2 (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7259006 | 0.87 | TACR2 (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7259967 | 0.87 | TACR2 (0.44) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL6688720 | 0.85 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5217929 | 0.81 | TACR2 (0.52) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7255339 | 0.81 | TACR2 (0.42) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7255344 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7259950 | 0.79 | FDPS (0.51) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL7255340 | 0.78 | AKR1B1 (0.68) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070239-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | disclosed |