Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259967 | 1.00 | TACR2 (0.44) | TACR2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL7256181 | 1.00 | TACR2 (0.44) | TACR2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL7259006 | 1.00 | TACR2 (0.44) | TACR2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL7255337 | 0.87 | ALDH1A1 (0.45) | TACR2ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7255339 | 0.87 | TACR2 (0.42) | TACR2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL5217929 | 0.86 | TACR2 (0.52) | TACR2RXRARXRBRXRGALDH1A1 | |
| SCHEMBL7255761 | 0.84 | RXRA (0.43) | RXRARXRBRXRGRAB9ANPC1 | |
| SCHEMBL7258851 | 0.84 | RXRA (0.43) | RXRARXRBRXRGRAB9ANPC1 | |
| SCHEMBL6688720 | 0.81 | ALDH1A1 (0.58) | TACR2ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL7259002 | 0.81 | RXRA (0.47) | RXRARXRBRXRGSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070238-A1 | THIAZOLIDINE ANTIFUNGAL AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | claimed |
| WO-2003070238-A1 | THIAZOLIDINE ANTIFUNGAL AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | disclosed |