Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217929 | 0.93 | TACR2 (0.52) | TACR2MAOAMAOBRXRARXRB | |
| SCHEMBL9077155 | 0.87 | TACR2 (0.54) | TACR2MAOAMAOBAKR1C3ALDH1A1 | |
| SCHEMBL5213944 | 0.87 | TACR2 (0.54) | TACR2MAOAMAOBAKR1C3ALDH1A1 | |
| SCHEMBL29721221 | 0.87 | TACR2 (0.54) | TACR2MAOAMAOBAKR1C3ALDH1A1 | |
| SCHEMBL5218024 | 0.86 | AKR1C3 (0.56) | TACR2MAOAMAOBAKR1C3ALDH1A1 | |
| SCHEMBL7255344 | 0.86 | ALDH1A1 (0.48) | TACR2ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL3954569 | 0.84 | RXRA (0.52) | TACR2MAOAMAOBRXRARXRB | |
| SCHEMBL7255559 | 0.83 | C5AR1 (0.46) | RXRARXRBRXRGMRGPRX4 | |
| SCHEMBL5219137 | 0.83 | TACR2 (0.67) | TACR2MAOAMAOBAKR1C3ALDH1A1 | |
| SCHEMBL4576841 | 0.82 | FDPS (0.57) | TACR2MAOAMAOBAKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070238-A1 | THIAZOLIDINE ANTIFUNGAL AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | claimed |
| WO-2003070238-A1 | THIAZOLIDINE ANTIFUNGAL AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | disclosed |