Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415057 | 0.89 | ALDH1A1 (0.61) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL8372531 | 0.87 | HSD17B3 (0.62) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| Umbelliferone SCHEMBL3762137 | 0.84 | HSD17B3 (0.70) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL4209990 | 0.83 | SLC18A1 (0.60) | HSD17B3ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL300152 | 0.83 | NQO1 (0.53) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| Diethylamine SCHEMBL28338576 | 0.81 | RECQL (0.51) | HSD17B3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5459900 | 0.80 | CA12 (0.61) | HSD17B3ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL18138409 | 0.80 | NQO1 (0.58) | HSD17B3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL30486066 | 0.80 | CA12 (0.61) | HSD17B3ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL24523102 | 0.80 | NQO1 (0.50) | HSD17B3KDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176494-A1 | Novel coumarin and chromene compounds and methods of preparation and use thereof for treating or preventing viral infections | ADVANCED LIFE SCIENCES, INC. | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176494-A1 | Novel coumarin and chromene compounds and methods of preparation and use thereof for treating or preventing viral infections | HAVCR2, PROC, CTRC | HSD17B3 633/4885KDM4E 3488/4885ALDH1A1 2199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.