Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257013 | 0.92 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL7256885 | 0.92 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL7257012 | 0.92 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL8017544 | 0.73 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1MAPT | |
| SCHEMBL8017540 | 0.73 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1MAPT | |
| SCHEMBL8017542 | 0.73 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1MAPT | |
| SCHEMBL8023972 | 0.73 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1MAPT | |
| SCHEMBL7255719 | 0.71 | CRHBP (0.49) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL7256945 | 0.70 | CRHBP (0.43) | CRHBPCRHR2MEN1ALDH1A1MAPT | |
| SCHEMBL13170498 | 0.69 | CRHBP (0.44) | CRHBPCRHR2PTGS2PTGS1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080553-A1 | CYCLOPENTENE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-10-02 | — | — | WO | disclosed |