Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017540 | 1.00 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1LMNA | |
| SCHEMBL8017544 | 1.00 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1LMNA | |
| SCHEMBL8017542 | 1.00 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1LMNA | |
| SCHEMBL13170498 | 0.86 | CRHBP (0.44) | CRHBPCRHR2PTGS2PTGS1TP53 | |
| SCHEMBL13191513 | 0.83 | CRHBP (0.41) | CRHBPCRHR2PTGS2PTGS1MAPT | |
| SCHEMBL7256885 | 0.79 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1CYP1A2 | |
| SCHEMBL7257013 | 0.79 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1CYP1A2 | |
| SCHEMBL7257012 | 0.79 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1CYP1A2 | |
| SCHEMBL3799748 | 0.77 | CRHBP (0.37) | CRHBPCRHR2MAPT | |
| SCHEMBL3799750 | 0.75 | CRHBP (0.35) | CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828614-B1 | ARTICLE INTENDED FOR MARKING AND A METHOD OF MARKING IT | BICC PLC (GB) | 2000-01-05 | — | — | EP | disclosed |
| EP-0828614-A1 | METHOD OF MARKING AN ARTICLE | BICC Public Limited Company (GB) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037369-A1 | METHOD OF MARKING AN ARTICLE | BICC PUBLIC LIMITED COMPANY (GB) | 1996-11-28 | — | — | WO | disclosed |