Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.72 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.72 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256885 | 1.00 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL7257012 | 1.00 | CRHBP (0.72) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL7255647 | 0.92 | CRHBP (0.62) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL8017542 | 0.79 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1CYP3A4 | |
| SCHEMBL8017544 | 0.79 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1CYP3A4 | |
| SCHEMBL8023972 | 0.79 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1CYP3A4 | |
| SCHEMBL8017540 | 0.79 | CRHBP (0.50) | CRHBPCRHR2PTGS2PTGS1CYP3A4 | |
| SCHEMBL7255719 | 0.78 | CRHBP (0.49) | CRHBPCRHR2PTGS2PTGS1MEN1 | |
| SCHEMBL7256945 | 0.74 | CRHBP (0.43) | CRHBPCRHR2MEN1CYP3A4KMT2A | |
| SCHEMBL25834334 | 0.73 | CRHBP (0.57) | CRHBPCRHR2MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080553-A1 | CYCLOPENTENE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2003-10-02 | — | — | WO | disclosed |