SCHEMBL725628

SCHEMBL725628

Fc1ccc(OCCCOc2ccc(F)cc2I)c(I)c1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.41
PLAU P00749 1/20 0.41
ST14 Q9Y5Y6 1/20 0.41
HTR2C P28335 4/20 0.36
HTR2A P28223 3/20 0.36
PKM P14618 1/20 0.36
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTR2B P41595 2/20 0.35
DHFR P00374 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20516081 0.96 F2 (0.44) F2PLAUST14HTR2CHTR2A
SCHEMBL15065521 0.94 CYP1A2 (0.39) F2PLAUST14HTR2CHTR2A
SCHEMBL19382957 0.93 F2 (0.37) F2PLAUST14HTR2CHTR2A
SCHEMBL725616 0.89 S1PR4 (0.40) HTR2CHTR2B
SCHEMBL15847648 0.89 F2 (0.37) F2PLAUST14HTR2CHTR2A
SCHEMBL29066374 0.89 CYP1A2 (0.44) F2PLAUST14HTR2CHTR2A
SCHEMBL23537567 0.87 F2 (0.42) F2PLAUST14HTR2CHTR2A
SCHEMBL29913690 0.87 F2 (0.42) F2PLAUST14HTR2CHTR2A
SCHEMBL16333705 0.87 F2 (0.34) F2PLAUST14HTR2CHTR2A
SCHEMBL17861666 0.86 PKM (0.37) F2PLAUST14HTR2CHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565508-B2 Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-03 US disclosed
EP-3925989-B1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-07 EP disclosed
US-12497414-B2 Group III and Lanthanide bis-phenyl-phenoxy metal-ligand complexes DOW GLOBAL TECHNOLOGIES LLC (US) 2025-12-16 US disclosed
EP-4097151-B1 GROUP III AND LANTHANIDE BIS-PHENYL-PHENOXY METAL-LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-06 EP disclosed
CN-115298227-B Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2024-06-04 CN disclosed
EP-4332133-A2 GROUP III AND LANTHANIDE BIS-PHENYL-PHENOXY METAL-LIGAND COMPLEXES Dow Global Technologies LLC (US) 2024-03-06 EP disclosed
CN-111491942-B Metal-ligand complex, catalyst composition, and method for producing same 沙特基础工业爱思开NEXLENE私人有限公司 2024-01-12 CN disclosed
CN-117069749-A Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes 陶氏环球技术有限责任公司 2023-11-17 CN disclosed
US-20230183267-A1 GROUP III AND LANTHANIDE BIS-PHENYL-PHENOXY METAL-LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-15 US disclosed
US-20230183267-A1 GROUP III AND LANTHANIDE BIS-PHENYL-PHENOXY METAL-LIGAND COMPLEXES DOW GLOBAL TECHNOLOGIES LLC (US) 2023-06-15 US disclosed
US-9029487-B2 Process for polymerizing a polymerizable olefin and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-12 US disclosed
US-9029487-B2 Process for polymerizing a polymerizable olefin and catalyst therefor DOW GLOBAL TECHNOLOGIES LLC (US) 2015-05-12 US disclosed
WO-2014210333-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-31 WO disclosed
WO-2014210333-A1 MOLECULAR WEIGHT CONTROL OF POLYOLEFINS USING HALOGENATED BIS-PHENYLPHENOXY CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-31 WO disclosed
EP-2609123-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR Dow Global Technologies LLC (US) 2013-07-03 EP disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
US-20130144018-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2013-06-06 US disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed
WO-2012027448-A1 PROCESS FOR POLYMERIZING A POLYMERIZABLE OLEFIN AND CATALYST THEREFOR DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565508-B2 Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes SCO2, CBR3, SOD1 F2 3337/4885PLAU 4205/4885ST14 3006/4885
US-12497414-B2 Group III and Lanthanide bis-phenyl-phenoxy metal-ligand complexes SSB, SOD1, LGALS3 F2 1069/4885PLAU 1824/4885ST14 2150/4885
US-20230183267-A1 GROUP III AND LANTHANIDE BIS-PHENYL-PHENOXY METAL-LIGAND COMPLEXES SSB, SOD1, LGALS3 F2 953/4885PLAU 1783/4885ST14 2219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.