SCHEMBL15065521

SCHEMBL15065521

Fc1ccc(OCCOc2ccc(F)cc2I)c(I)c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
F2 P00734 1/20 0.38
PLAU P00749 1/20 0.38
ST14 Q9Y5Y6 1/20 0.38
HTR2C P28335 4/20 0.37
HTR2A P28223 3/20 0.37
PKM P14618 1/20 0.37
S1PR4 O95977 1/20 0.36
HTR2B P41595 2/20 0.36
KLK1 P06870 1/20 0.35
TRPA1 O75762 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20516081 0.94 F2 (0.44) TDP1L3MBTL1F2PLAUST14
SCHEMBL725628 0.94 F2 (0.41) TDP1L3MBTL1F2PLAUST14
SCHEMBL19373833 0.89 L3MBTL1 (0.42) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL28448358 0.88 HTR2C (0.48) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL17861666 0.88 PKM (0.37) F2PLAUST14HTR2CHTR2A
SCHEMBL17801580 0.87 PKM (0.37) F2PKMKLK1TRPA1
SCHEMBL15847648 0.87 F2 (0.37) TDP1L3MBTL1F2PLAUST14
SCHEMBL19382957 0.87 F2 (0.37) TDP1L3MBTL1F2PLAUST14
SCHEMBL29066374 0.87 CYP1A2 (0.44) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1
SCHEMBL16340047 0.86 TRPA1 (0.35) CYP1A2CYP2D6CYP2C19TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227304-B1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-29 EP disclosed
EP-3227304-B1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-01-29 EP disclosed
EP-2797963-B1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-03 EP disclosed
EP-2797963-B1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2019-07-03 EP disclosed
US-10301412-B2 Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-28 US disclosed
US-10301412-B2 Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers DOW GLOBAL TECHNOLOGIES LLC (US) 2019-05-28 US disclosed
EP-3227304-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS Dow Global Technologies LLC (US) 2017-10-11 EP disclosed
US-20170267796-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2017-09-21 US disclosed
US-20170267796-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC 2017-09-21 US disclosed
US-9601231-B2 Hyperbranched olefin oil-based dielectric fluid DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-21 US disclosed
US-9601231-B2 Hyperbranched olefin oil-based dielectric fluid DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-21 US disclosed
US-9601231-B2 Hyperbranched olefin oil-based dielectric fluid DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-21 US disclosed
WO-2016089935-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-09 WO disclosed
WO-2016089935-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-06-09 WO disclosed
US-20140330056-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-06 US disclosed
US-20140330056-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-06 US disclosed
US-20140330056-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-06 US disclosed
EP-2797963-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID Dow Global Technologies LLC (US) 2014-11-05 EP disclosed
WO-2013101376-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed
WO-2013101376-A1 HYPERBRANCHED OLEFIN OIL-BASED DIELECTRIC FLUID DOW GLOBAL TECHNOLOGIES LLC (US) 2013-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170267796-A1 FIVE-COORDINATE BIS-PHENYLPHENOXY CATALYSTS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS PARG, AP1M1, BZW1 CYP1A2 680/4885CYP2D6 385/4885CYP2C19 364/4885
US-10301412-B2 Five-coordinate bis-phenylphenoxy catalysts for the preparation of ethylene-based polymers PARG, AP1M1, BZW1 CYP1A2 680/4885CYP2D6 385/4885CYP2C19 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.