Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256356 | 0.82 | EGFR (0.58) | TACR3ALDH1A1HTTSMN1; SMN2EGFR | |
| SCHEMBL9569932 | 0.81 | ADORA2A (0.58) | TACR3ALDH1A1EGFRKDM4ELMNA | |
| SCHEMBL21676260 | 0.74 | EGFR (0.54) | ALDH1A1EGFRHPGDTSHR | |
| SCHEMBL4173835 | 0.74 | CTSV (0.53) | TACR3ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL7257209 | 0.74 | TACR3 (0.51) | TACR3ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL19452099 | 0.73 | TACR3 (0.50) | TACR3ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL10988800 | 0.72 | MAPK1 (0.54) | TACR3ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL5438509 | 0.72 | MEN1 (0.51) | ALDH1A1HTTSMN1; SMN2EGFRKDM4E | |
| SCHEMBL701920 | 0.71 | TAS1R3 (0.48) | EGFR | |
| SCHEMBL14284682 | 0.71 | TACR3 (0.53) | TACR3ALDH1A1HTTNCOA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MELACURE THERAPEUTICS AB (SE) | 2003-10-16 | — | — | US | claimed |
| EP-1254114-A2 | MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | Melacure Therapeutics AB (SE) | 2002-11-06 | — | — | EP | claimed |
| WO-2001055106-A2 | NOVEL MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| EP-1254114-A2 | MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | Melacure Therapeutics AB (SE) | 2002-11-06 | — | — | EP | disclosed |
| WO-2001055106-A2 | NOVEL MELANOCORTIN RECEPTOR AGONISTS AND ANTAGONISTS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195212-A1 | Novel melanocortin receptor agonists and antagonists | MC1R, MC5R, MC4R | TACR3 255/4885ALDH1A1 2823/4885HTT 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.