Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | TK2 | O00142 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355175 | 0.90 | TK1 (0.40) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL14785922 | 0.76 | PYGM (0.35) | LMNATYMPTK2 | |
| SCHEMBL3345508 | 0.76 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL12658380 | 0.76 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL8904559 | 0.76 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL1825757 | 0.76 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL29041599 | 0.75 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL16042097 | 0.75 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL28072298 | 0.75 | TK1 (0.43) | TK1ALDH1A1LMNAALBPOLB | |
| SCHEMBL27349255 | 0.75 | TK1 (0.42) | TK1ALDH1A1LMNAALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6635753-B1 | Compound as precipitated solvate selected from stavudine N,N-dimethylacetamide solvate, stavudine N,N-dimethylacrylamide solvate, and stavudine N,N-dimethylpropionamide solvate | BRANTFORD CHEMICALS INC. (CA) | 2003-10-21 | — | — | US | disclosed |