Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | BID | P55957 | 2/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468314 | 0.73 | PARP1 (0.42) | PARP1GPR84ABCB1 | |
| SCHEMBL792961 | 0.69 | HTR6 (0.35) | BIDBCL2L1MCL1BAK1 | |
| SCHEMBL10181242 | 0.69 | MMP2 (0.46) | PTGDR2 | |
| SCHEMBL11143339 | 0.66 | LIPG (0.50) | BIDBCL2L1MCL1BAK1 | |
| SCHEMBL16111391 | 0.66 | TDP1 (0.40) | GPR84ABCB1BIDBCL2L1MCL1 | |
| SCHEMBL11137516 | 0.66 | LIPG (0.51) | BIDBCL2L1MCL1BAK1 | |
| SCHEMBL8520962 | 0.66 | LIPG (0.53) | BIDBCL2L1MCL1BAK1 | |
| SCHEMBL28050271 | 0.66 | LIPG (0.50) | BIDBCL2L1MCL1BAK1 | |
| SCHEMBL906515 | 0.65 | LIPG (0.53) | BIDBCL2L1MCL1BAK1 | |
| SCHEMBL7705267 | 0.65 | LIPG (0.53) | BIDBCL2L1MCL1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109059-A1 | COMPOUNDS FOR TREATMENT OF CANCER | GTX, INC. (US) | 2011-09-09 | — | — | WO | disclosed |