Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | MGAM | O43451 | 3/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256736 | 0.84 | CNR2 (0.40) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7536631 | 0.81 | CASP3 (0.47) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7261259 | 0.81 | EGFR (0.48) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7257604 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7261248 | 0.79 | ALDH1A1 (0.46) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7256749 | 0.79 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7532023 | 0.79 | EGFR (0.48) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7256772 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7261275 | 0.78 | ALDH1A1 (0.45) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 | |
| SCHEMBL7260717 | 0.77 | ALDH1A1 (0.48) | ALDH1A1CYP3A4KDM4EHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645983-B1 | Heterocyclic imines such as 3-(4-methoxyphenyl)-1,4-dihydro-4 -quinolinone, used as anticarcinogenic agents having cytolysis efficiency; side effect reduction | LABORATOIRE L. LAFON (FR) | 2003-11-11 | — | — | US | disclosed |
| WO-2002022074-A2 | USE OF 2- AND 4- QUINOLONES FOR INHIBITING INTIMAL NEO-PROLIFERATION | LABORATOIRE L. LAFON (FR) | 2002-03-21 | — | — | WO | disclosed |