Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047670 | 0.92 | MAPT (0.59) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL9424973 | 0.84 | ALDH1A1 (0.53) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11527133 | 0.79 | KDM4E (0.50) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL3531884 | 0.78 | ALDH1A1 (0.49) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL28720960 | 0.77 | MAPT (0.67) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL27546693 | 0.76 | KDM4E (0.56) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL28301754 | 0.75 | KDM4E (0.55) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL6757708 | 0.74 | MAPT (0.67) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL27356901 | 0.74 | ALDH1A1 (0.55) | MAPTKDM4ETDP1ALDH1A1HPGD | |
| SCHEMBL222908 | 0.74 | NR4A1 (0.60) | MAPTKDM4EALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015031614-A1 | SOLUBLE CMET ASSAY | ABBVIE INC. (US) | 2015-03-05 | — | — | WO | disclosed |
| EP-2655415-A2 | TRI-VARIABLE DOMAIN BINDING PROTEINS AND USES THEREOF | AbbVie Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| EP-2654792-A2 | HALF IMMUNOGLOBULIN BINDING PROTEINS AND USES THEREOF | AbbVie Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| EP-2590671-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | Abbott Laboratories (US) | 2013-05-15 | — | — | EP | disclosed |
| US-20130029353-A1 | AUTOANTIBODY ENHANCED IMMUNOASSAYS AND KITS | ABBOTT LABORATORIES (US) | 2013-01-31 | — | — | US | disclosed |
| EP-2493924-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | Abbott Laboratories (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2473524-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | Abbott Laboratories (US) | 2012-07-11 | — | — | EP | disclosed |
| WO-2012088302-A2 | HALF IMMUNOGLOBULIN BINDING PROTEINS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088290-A2 | TRI-VARIABLE DOMAIN BINDING PROTEINS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-06-28 | — | — | WO | disclosed |
| EP-2459729-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | Abbott Laboratories (US) | 2012-06-06 | — | — | EP | disclosed |
| WO-2012006490-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2011163558-A1 | MATERIALS AND METHODS FOR ASSAY OF ANTI-HEPATITIS C VIRUS (HCV) ANTIBODIES | ABBOTT LABORATORIES (US) | 2011-12-29 | — | — | WO | disclosed |
| EP-2297209-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | Abbott Laboratories (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2011028811-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2011-03-10 | — | — | WO | disclosed |
| EP-2282769-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | Abbott Laboratories (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2011014659-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2011-02-03 | — | — | WO | disclosed |
| WO-2009149189-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009134776-A2 | DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-11-05 | — | — | WO | disclosed |
| WO-2008124749-A1 | ACRIDINIUM PHENYL ESTERS USEFUL IN THE ANALYSIS OF BIOLOGICAL SAMPLES | ABBOTT LABORATORIES (US) | 2008-10-16 | — | — | WO | disclosed |