Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222908 | 0.91 | NR4A1 (0.60) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| Acridine SCHEMBL29774329 | 0.89 | NR4A1 (0.58) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| Hydrochloric Acid SCHEMBL9083721 | 0.89 | NR4A1 (0.58) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| SCHEMBL8850857 | 0.89 | NR4A1 (0.58) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| Acridine SCHEMBL31147690 | 0.89 | NR4A1 (0.58) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| Water SCHEMBL7769203 | 0.89 | NR4A1 (0.58) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| SCHEMBL725676 | 0.84 | MAPT (0.51) | ALDH1A1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL27356901 | 0.80 | ALDH1A1 (0.55) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| SCHEMBL5352931 | 0.79 | ALDH1A1 (0.53) | ALDH1A1NR4A1NR4A2NR4A3KMT2A | |
| SCHEMBL3296316 | 0.78 | KMT2A (0.54) | ALDH1A1NR4A1NR4A2NR4A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290936-A | Indicators or labels for antibodies or medical diagnosis | LONDON DIAGNOSTICS, INC. (US) | 1994-03-01 | — | — | US | disclosed |
| US-5284951-A | Aryl ester, thioester or amide of carboxylic acid substituted heterocyclic ring; quaternary compounds | LONDON DIAGNOSTICS, INC. (US) | 1994-02-08 | — | — | US | disclosed |
| US-5283334-A | Side-chain functional chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-02-01 | — | — | US | disclosed |