⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614328 | 0.83 | — | — | |
| SCHEMBL27771064 | 0.81 | TDO2 (0.30) | — | |
| SCHEMBL28049044 | 0.81 | — | — | |
| SCHEMBL2517442 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL27979361 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL28180007 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL14562749 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL7996476 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL28807262 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL6292615 | 0.78 | MMP3 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2870159-B1 | APPLICATION OF ß-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | BIOLITEC UNTERNEHMENSBETEILIGUNGS II AG (AT) | 2017-06-28 | — | — | EP | disclosed |
| US-9156849-B2 | Application of β-functionalized dihydroxy-chlorins for PDT | BIOLITEC PHARMA MARKETING LTD (MY) | 2015-10-13 | — | — | US | disclosed |
| US-20130041307-A1 | APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT | CERAMOPTEC INDUSTRIES, INC. | 2013-02-14 | — | — | US | disclosed |
| EP-0804439-B1 | BETA, BETA '-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM BETA ,BETA '-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES | UNIV BRITISH COLUMBIA (CA) | 2003-09-17 | — | — | EP | disclosed |
| US-5831088-A | OSMYLATION | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 1998-11-03 | — | — | US | disclosed |
| US-5648485-A | PORPHYRIN COMPOUNDS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 1997-07-15 | — | — | US | disclosed |