Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.46 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256811 | 0.83 | MAPT (0.54) | ALDH1A1MEN1KMT2AHTTHTR2A | |
| SCHEMBL6701277 | 0.77 | DRD2 (0.66) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 | |
| SCHEMBL2232683 | 0.75 | GAA (0.62) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 | |
| SCHEMBL6699610 | 0.73 | ALDH1A1 (0.46) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 | |
| SCHEMBL2744427 | 0.73 | HTR2A (0.69) | ITGB3ITGA2BHTR2AHTR2CHTR2B | |
| SCHEMBL3128886 | 0.73 | CHRNA7 (0.58) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 | |
| SCHEMBL6698448 | 0.72 | ALDH1A1 (0.61) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL9742137 | 0.72 | HTR2A (0.67) | ITGB3ITGA2BHTR2AHTR2CHTR2B | |
| SCHEMBL6550343 | 0.72 | CHRNA7 (0.54) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 | |
| SCHEMBL7253167 | 0.72 | MEN1 (0.51) | CHRNA7CHRNA10CHRNA9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003048121-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | disclosed |