Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.56 |
| ▸ | JAK1 | P23458 | 2/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.56 |
| ▸ | GRK2 | P25098 | 2/20 | 0.56 |
| ▸ | GRK5 | P34947 | 2/20 | 0.56 |
| ▸ | GRK1 | Q15835 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259291 | 0.91 | ROCK1 (0.58) | JAK2JAK1ROCK1GRK2GRK5 | |
| SCHEMBL7255625 | 0.85 | NPC1 (0.57) | JAK2JAK1ROCK1GRK2GRK5 | |
| SCHEMBL7255709 | 0.81 | JAK2 (0.58) | JAK2JAK1ROCK1NPC1RAB9A | |
| SCHEMBL7261149 | 0.78 | NPC1 (0.68) | JAK2JAK1ROCK1NPC1RAB9A | |
| SCHEMBL6768877 | 0.78 | PTK2 (0.64) | JAK2JAK1ROCK1NPC1RAB9A | |
| SCHEMBL7255808 | 0.78 | JAK2 (0.57) | JAK2JAK1ROCK1NPC1RAB9A | |
| SCHEMBL7257003 | 0.76 | NPC1 (0.51) | JAK2JAK1ROCK1GRK2GRK5 | |
| SCHEMBL15764656 | 0.76 | NPC1 (0.81) | JAK2JAK1ROCK1NPC1RAB9A | |
| SCHEMBL7255640 | 0.76 | JAK2 (0.52) | JAK2JAK1ROCK1GRK2GRK5 | |
| SCHEMBL7259294 | 0.76 | NPC1 (0.50) | JAK2JAK1ROCK1GRK2GRK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002518-A1 | NOVEL 2,4-DIFLUOROBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | DONG HWA PHARM. IND. CO., LTD. (KR) | 2003-01-09 | — | — | WO | disclosed |