⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550427 | 0.62 | FAAH (0.37) | — | |
| SCHEMBL8630411 | 0.62 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL9588660 | 0.62 | ENPP1 (0.33) | — | |
| SCHEMBL5209322 | 0.61 | CTSK (0.31) | — | |
| SCHEMBL4218754 | 0.60 | — | — | |
| SCHEMBL5871666 | 0.59 | — | — | |
| SCHEMBL4278928 | 0.58 | — | — | |
| SCHEMBL27599203 | 0.58 | — | — | |
| SCHEMBL18936266 | 0.56 | LMNA (0.31) | — | |
| SCHEMBL7261343 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030096828-A1 | Cyclic amide compound | KOWA CO., LTD. (JP) | 2003-05-22 | — | — | US | disclosed |
| US-6448242-B1 | COMPOUND HAVING A STRONG INHIBITORY EFFECT ON THE PRODUCTION OF AN IGE ANTIBODY; ANTIALLERGENS | KOWA CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |