Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569570 | 0.86 | GBA1 (0.59) | GAAMEN1KMT2AALDH1A1CA2 | |
| SCHEMBL27771985 | 0.84 | GBA1 (0.53) | MEN1KMT2AALDH1A1GBA1 | |
| SCHEMBL31586722 | 0.81 | ALDH1A1 (0.47) | GAAMEN1KMT2AALDH1A1GBA1 | |
| SCHEMBL2934786 | 0.78 | ALDH1A1 (0.67) | GAASIGMAR1CYP19A1ALDH1A1MMP1 | |
| SCHEMBL6597702 | 0.76 | GAA (0.49) | GAASIGMAR1NHERF1MEN1KMT2A | |
| SCHEMBL3020463 | 0.76 | ALDH1A1 (0.68) | GAASIGMAR1CYP19A1ALDH1A1MMP1 | |
| SCHEMBL6321465 | 0.76 | CA1 (0.52) | GAASIGMAR1CYP19A1ALDH1A1MMP1 | |
| SCHEMBL3412348 | 0.76 | CA1 (0.52) | GAASIGMAR1CYP19A1ALDH1A1MMP1 | |
| SCHEMBL6324078 | 0.76 | SIGMAR1 (0.51) | GAASIGMAR1CYP19A1ALDH1A1MMP1 | |
| SCHEMBL3412102 | 0.76 | CA1 (0.52) | GAASIGMAR1CYP19A1ALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346994-A1 | CHOLESTEROL BIOSYNTHESIS INHIBITORS CONTAINING AS THE ACTIVE INGREDIENT TRICYCLIC SPIRO COMPOUNDS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |