SCHEMBL6604832

SCHEMBL6604832

CC(C)CCCC(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.64
TDP1 Q9NUW8 3/20 0.64
MAPT P10636 3/20 0.64
LMNA P02545 2/20 0.64
HDAC1 Q13547 5/20 0.58
HDAC8 Q9BY41 5/20 0.58
HDAC3 O15379 1/20 0.58
HDAC4 P56524 1/20 0.58
HDAC7 Q8WUI4 1/20 0.58
HDAC2 Q92769 1/20 0.58
HDAC10 Q969S8 1/20 0.58
HDAC11 Q96DB2 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
HDAC9 Q9UKV0 1/20 0.58
HDAC5 Q9UQL6 1/20 0.58
NPC1 O15118 1/20 0.56
CASP3 P42574 1/20 0.56
RAB9A P51151 1/20 0.56
SENP8 Q96LD8 1/20 0.56
SENP7 Q9BQF6 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12464189 0.94 TDP1 (0.68) L3MBTL1TDP1MAPTLMNAHDAC1
SCHEMBL17867451 0.93 L3MBTL1 (0.71) L3MBTL1TDP1MAPTLMNAHDAC1
SCHEMBL1122004 0.93 L3MBTL1 (0.71) L3MBTL1TDP1MAPTLMNAHDAC1
Benzene SCHEMBL27311002 0.88 TRPA1 (0.58) L3MBTL1TDP1MAPTLMNAHDAC1
SCHEMBL725762 0.88 TRPA1 (0.58) L3MBTL1TDP1MAPTLMNAHDAC1
SCHEMBL10420753 0.87 L3MBTL1 (0.62) L3MBTL1TDP1MAPTLMNAHDAC1
SCHEMBL31351852 0.86 KMT2A (0.52) L3MBTL1TDP1MAPTLMNAHDAC1
SCHEMBL23782435 0.85 MMP1 (0.56) L3MBTL1TDP1MAPTLMNANPC1
SCHEMBL5696497 0.85 L3MBTL1 (0.60) L3MBTL1TDP1MAPTLMNAHDAC1
SCHEMBL28613349 0.85 L3MBTL1 (0.60) L3MBTL1TDP1MAPTLMNAHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254432-A2 Method of preparing alpha-arylalkanoic esters Mallinckrodt, Inc. (a Delaware corporation) (US) 1988-01-27 EP claimed
JP-57163337-A None JP disclosed
US-20260079169-A1 VOLATILE ORGANIC COMPOUNDS AS MARKERS FOR CELLULAR COMMUNICATION TECHNION RES & DEV FOUNDATION (IL) 2026-03-19 US disclosed
US-20240238461-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF JANSSEN BIOTECH, INC. 2024-07-18 US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-9579325-B2 Modulators of TNF-α signaling GENZYME CORPORATION (US) 2017-02-28 US disclosed
US-9579325-B2 Modulators of TNF-α signaling GENZYME CORPORATION (US) 2017-02-28 US disclosed
US-20150126512-A1 Modulators Of TNF-Alpha Signaling GENZYME CORPORATION (US) 2015-05-07 US disclosed
US-8921547-B2 Modulators of TNF-α signaling GENZYME CORPORATION (US) 2014-12-30 US disclosed
US-20130310388-A1 Modulators of TNF-Alpha Signaling GENZYME CORPORATION (US) 2013-11-21 US disclosed
WO-1995014012-A1 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS PARKE, DAVIS & COMPANY (US) 1995-05-26 WO disclosed
WO-1995014011-A2 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS PARKE, DAVIS & COMPANY (US) 1995-05-26 WO disclosed
US-5250546-A Administering as therapy for spastic paralysis; glutamic acid blocking agent; agricultural chemicals NIPPON CHEMIPHAR CO., LTD. (JP) 1993-10-05 US disclosed
EP-0177245-B1 AMINO-ALCOHOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION NIPPON CHEMIPHAR CO., LTD. (JP) 1991-04-10 EP disclosed
EP-0254432-A2 Method of preparing alpha-arylalkanoic esters Mallinckrodt, Inc. (a Delaware corporation) (US) 1988-01-27 EP disclosed
EP-0048136-B1 PROCESS FOR PREPARING ALPHA-AROMATIC GROUP SUBSTITUTED ALKANOIC ACIDS OR ESTERS THEREOF SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1986-06-11 EP disclosed
EP-0177245-A2 Amino-alcohol derivatives and processes for their preparation NIPPON CHEMIPHAR CO., LTD. (JP) 1986-04-09 EP disclosed
JP-S57163337-A PREPARATION OF PROPIONIC ACID DERIVATIVE KYOWA HAKKO KOGYO CO LTD 1982-10-07 JP disclosed
US-4149413-A THERMOCHROMIC THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHER IRELAND (GB) 1979-04-17 US disclosed
US-4071448-A FORMALDEHYDE, HEATING IN OXYGEN, DECOMPOSITION, NONTOXIC PRODUCTS MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1978-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873291-B2 Quinoline cGAS antagonist compounds CGAS, GLS2, GLS L3MBTL1 4285/4885TDP1 69/4885MAPT 3235/4885
US-20260079169-A1 VOLATILE ORGANIC COMPOUNDS AS MARKERS FOR CELLULAR COMMUNICATION BCL2, BAX, EPCAM L3MBTL1 99/4885TDP1 3602/4885MAPT 3088/4885
US-20240238461-A1 MACROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF BDNF, CD47, MAG L3MBTL1 2509/4885TDP1 1821/4885MAPT 140/4885
US-20150126512-A1 Modulators Of TNF-Alpha Signaling TNF, TNFRSF1A, TNFRSF9 L3MBTL1 4543/4885TDP1 3459/4885MAPT 3308/4885
US-20130310388-A1 Modulators of TNF-Alpha Signaling TNF, TNFRSF1A, TNFRSF9 L3MBTL1 4543/4885TDP1 3459/4885MAPT 3308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.