SCHEMBL725808

SCHEMBL725808

CS(=O)(=O)c1ccc(C(=O)C2(N3CCCC3)CCCCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.58
ALDH1A1 P00352 3/20 0.45
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.42
DUSP3 P51452 1/20 0.40
PTPN5 P54829 1/20 0.40
PTPN11 Q06124 1/20 0.40
GLA P06280 1/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
GCK P35557 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727273 0.80 MEN1 (0.39) HTTALDH1A1NPC1MAPTRAB9A
SCHEMBL16576960 0.79 ALDH1A1 (0.56) HTTALDH1A1NPC1MAPTRAB9A
SCHEMBL727241 0.78 MEN1 (0.49) HTTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL727265 0.78 MEN1 (0.49) HTTALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL727190 0.76 HTT (0.47) HTTKMT2A
SCHEMBL13863437 0.75 ALDH1A1 (0.41) HTTALDH1A1NPC1MAPTKMT2A
SCHEMBL7487934 0.75 HTT (0.46) HTTSMN1; SMN2KMT2A
SCHEMBL11896695 0.75 RAB9A (0.46) HTTALDH1A1NPC1MAPTRAB9A
SCHEMBL9561706 0.72 ALDH1A1 (0.51) HTTALDH1A1NPC1MAPTRAB9A
SCHEMBL11896646 0.71 MEN1 (0.37) HTTALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
CN-102958909-B metal-free bleaching compositions 巴斯夫欧洲公司 2016-11-09 CN disclosed
US-20130117941-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-16 US disclosed
US-20130117941-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-16 US disclosed
US-20130117941-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-16 US disclosed
EP-2585431-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-01 EP disclosed
CN-102958909-A metal-free bleaching compositions BASF S E 2013-03-06 CN disclosed
WO-2012000846-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2012-01-05 WO disclosed
WO-2012000846-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2012-01-05 WO disclosed