SCHEMBL9561706

SCHEMBL9561706

O=C(c1ccccc1)C12CCCN1CCC2

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.51
TP53 P04637 2/20 0.51
TSHR P16473 2/20 0.43
HPGD P15428 3/20 0.43
LMNA P02545 2/20 0.42
OPRM1 P35372 1/20 0.40
OPRL1 P41146 1/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
STAT1 P42224 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 1/20 0.40
HSD11B1 P28845 2/20 0.39
USP2 O75604 1/20 0.39
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16576960 0.93 ALDH1A1 (0.56) ALDH1A1TP53TSHRHPGDLMNA
SCHEMBL11896695 0.75 RAB9A (0.46) ALDH1A1TP53TSHRHPGDLMNA
SCHEMBL27518012 0.73 HPGD (0.42) ALDH1A1TP53TSHRHPGDLMNA
SCHEMBL727241 0.73 MEN1 (0.49) ALDH1A1TP53TSHRHPGDLMNA
SCHEMBL727265 0.73 MEN1 (0.49) ALDH1A1TP53TSHRHPGDLMNA
SCHEMBL13863437 0.73 ALDH1A1 (0.41) ALDH1A1TP53TSHRHPGDOPRM1
SCHEMBL727273 0.72 MEN1 (0.39) ALDH1A1TP53TSHRHPGDOPRM1
SCHEMBL725808 0.72 HTT (0.58) ALDH1A1NPC1MAPTRAB9ASMN1; SMN2
SCHEMBL20576671 0.71 LMNA (0.55) ALDH1A1TSHRHPGDLMNAMAPT
SCHEMBL14061763 0.71 KDM1A (0.35) ALDH1A1TP53TSHRHSD11B1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0558321-A1 Antivirally active N-cycloalkyl alkanol compounds SANWA KAGAKU KENKYUSHO CO., LTD. (JP) 1993-09-01 EP disclosed