Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404582 | 0.93 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1LMNA | |
| Bromide SCHEMBL6402414 | 0.93 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6404090 | 0.91 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6401544 | 0.79 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6400682 | 0.73 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6403273 | 0.73 | LMNA (0.49) | KMT2ALMNASCN9A | |
| SCHEMBL7256300 | 0.72 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6401550 | 0.70 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6403296 | 0.69 | HDAC3 (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6401420 | 0.68 | CTSS (0.53) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003024923-A1 | SULFONAMIDE COMPOUNDS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-03-27 | — | — | WO | claimed |