Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256300 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6401550 | 0.85 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6403319 | 0.85 | USP30 (0.45) | KMT2AMAPTALDH1A1LMNARAB9A | |
| SCHEMBL6401358 | 0.83 | CTSS (0.45) | RAB9ANPC1 | |
| SCHEMBL6402653 | 0.81 | CTSS (0.47) | MAPTLMNARAB9ANPC1 | |
| SCHEMBL6404582 | 0.80 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6404090 | 0.80 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| Bromide SCHEMBL6402414 | 0.80 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7258237 | 0.79 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6403176 | 0.77 | LPAR1 (0.45) | KMT2AALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900237-B2 | Sulfonamide compounds as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | claimed |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | Celera Corporation | 2003-08-21 | — | — | US | claimed |
| US-6900237-B2 | Sulfonamide compounds as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-05-31 | — | — | US | disclosed |
| US-6872690-B2 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH (US) | 2005-03-29 | — | — | US | disclosed |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | Celera Corporation | 2003-08-21 | — | — | US | disclosed |
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | WYETH | 2003-04-17 | — | — | US | disclosed |
| WO-2003024923-A1 | SULFONAMIDE COMPOUNDS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-03-27 | — | — | WO | disclosed |
| EP-1238586-A1 | Herbicidal 2-alkynyl-pyri(mi)dines | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073581-A1 | Herbicidal 2-alkynyl-pyri (mi) dines | DDT, AOX1, RIOX2 | MEN1 4023/4885KMT2A 1361/4885MAPT 4662/4885 |
| US-20030158231-A1 | Sulfonamide compounds as protease inhibitors | PRSS1, PRSS3, SPINT2 | MEN1 4533/4885KMT2A 2789/4885MAPT 2884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.