SCHEMBL7258244

SCHEMBL7258244

O=C(O)OC(=O)O.O=C(O)Oc1cc(OC(=O)O)cc(OC(=O)O)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
LMNA P02545 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 2/20 0.36
TTR P02766 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
BACE1 P56817 1/20 0.35
CYP19A1 P11511 1/20 0.33
NSD2 O96028 1/20 0.33
ELANE P08246 3/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31
INPPL1 O15357 1/20 0.31
INPP5A Q14642 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322525 0.91 LMNA (0.40) KDM4ELMNAMEN1KMT2ACYP3A4
SCHEMBL1001721 0.83 RXRA (0.42) KDM4ELMNAMEN1KMT2ACYP3A4
SCHEMBL1730357 0.81 CYP3A4 (0.43) KDM4ELMNAMEN1KMT2ACYP3A4
SCHEMBL1543224 0.79 ELANE (0.42) MEN1KMT2AMAPTELANEALDH1A1
SCHEMBL9001070 0.79 LMNA (0.47) KDM4ELMNAMEN1KMT2ACYP3A4
SCHEMBL1552646 0.79 CYP19A1 (0.43) KDM4ELMNAMEN1KMT2ACYP3A4
SCHEMBL8608872 0.79 NSD2 (0.48) KDM4ELMNAMEN1KMT2ACYP3A4
Terephthalic Acid SCHEMBL8736587 0.77 TSHR (0.57) KDM4EKMT2ATP53SMN1; SMN2ALDH1A1
SCHEMBL7371530 0.77 CYP4F2 (0.40) KDM4ELMNAMEN1KMT2ACYP3A4
SCHEMBL7190643 0.77 PKM (0.39) KDM4ELMNACYP3A4TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299467-A1 METHOD FOR PRODUCING NANOREINFORCED THERMOPLASTIC POLYMERS THÜRINGISCHES INSTITUT FÜR TEXTIL- UND KUNSTSTOFF-FORSCHUNG e.V. (DE) 2003-04-09 EP claimed
WO-2001096459-A1 METHOD FOR PRODUCING NANOREINFORCED THERMOPLASTIC POLYMERS Thüringisches Institut für Textil-und Kunststoff-Forschung E.V. (DE) 2001-12-20 WO claimed