Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262997 | 0.81 | ALDH1A1 (0.51) | KMT2AFAAHMEN1ALDH1A1MAPT | |
| SCHEMBL7258839 | 0.81 | ALDH1A1 (0.62) | FAAHDRD2DRD4ALDH1A1MAPT | |
| SCHEMBL11817061 | 0.80 | DRD4 (0.68) | KMT2AFAAHPKMDRD2DRD4 | |
| SCHEMBL7258289 | 0.80 | HTR2B (0.54) | KMT2ADRD2DRD4MEN1ALDH1A1 | |
| SCHEMBL11830305 | 0.79 | KMT2A (0.76) | KMT2AFAAHPKMDRD2DRD4 | |
| SCHEMBL7258434 | 0.79 | GFER (0.54) | KMT2AFAAHDRD2DRD4HDAC1 | |
| SCHEMBL7262647 | 0.77 | LMNA (0.56) | KMT2AMEN1ALDH1A1MAPTNPC1 | |
| SCHEMBL11819664 | 0.75 | DRD4 (0.65) | KMT2ADRD2DRD4MEN1ALDH1A1 | |
| SCHEMBL11821778 | 0.75 | KMT2A (0.64) | KMT2APKMDRD2DRD4ALDH1A1 | |
| SCHEMBL7258467 | 0.75 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |